Many families rely on home health care services or visit mental health clinics for compassionate care, so a dependable pharmacy makes everyday support easier.
Prescription refills should be simple, convenient, and free from long waits. The best pharmacies in Oklahoma City can give you direct access to skilled pharmacists who take the time to answer your questions and help with your prescriptions.
From regular refills to everyday health needs, the right local pharmacy can save you time and make managing your family’s health a little simpler. Now, here are the outstanding local spots worth checking out.
How much does a prescription cost in Oklahoma?
Prescription costs in Oklahoma vary by medication, insurance, and pharmacy, but common insured copays can range from around $10 to $75+ per month.
Some generic medications may cost about $10 to $20 through discount programs.
| Medication or Service Tier | Example Insured Cost | Uninsured / Cash Cost Guide |
| Generic Prescription Drugs | Up to $10 copay for a 30-day supply under applicable HealthChoice plans | Around $10-$20 for some medications through discount programs |
| Preferred Brand Medications | Up to $45 copay for a 30-day supply under applicable HealthChoice plans | Varies by medication |
| Non-Preferred Brand Medications | Up to $75 copay for a 30-day supply under applicable HealthChoice plans | Varies by medication |
| Specialty Medications | $10-$200 under applicable copay-based HealthChoice plans; other plans may use coinsurance | Varies by medication and treatment |
| Routine Flu Vaccination | $0 where covered without cost-sharing | Around $25-$50 |
1. Midtown Drug

Website: https://midtowndrugokc.com/
Address: 525 NW 11th Street, Suite 112
Contact: 405-768-1002 | [email protected]
Hours: Monday-Friday, 9:00 AM-6:00 PM; Saturday, 9:00 AM-12:00 PM
Standing in a long line when you already feel awful can drain your energy fast. Midtown Drug makes things easier as an independent community pharmacy offering custom compounding, mobile app access, and curbside pickup.
Their pharmacy team can prepare tailored medications when a prescription needs an alternative to standard options.
We spoke with a client who recently picked up medicine there, and they told us the staff brought the order out to their car in just two minutes.
They also found the smartphone app and automated interactive voice response system useful for staying connected with the pharmacy.
The main drawback is the limited Saturday schedule. They close at noon on Saturdays and stay closed on Sundays, so weekend errands can be tricky.
Customer Reviews
This place just makes it feel like a real business that cares about you
Best Pharmacy I’ve ever had. Got so tired of the large corporations that you stand in line, and they almost make you feel like a nuisance being there. This place just makes it feel like a real business that cares about you. Plus… they love dogs… it’s a win-win. Genuinely thankful I stumbled across this place while walking my dog. I recommend it to everyone now.
— Jay Roudybush | Google Review
The kindness and service of the entire staff is the best in Oklahoma
If you are looking for a pharmacist who is incredibly knowledgeable and cares deeply about his patients then this is the pharmacy for you. The kindness and service of the entire staff is the best in Oklahoma. Thankyou to Dr. Phong and his staff for providing such great patient care!
— Kristin Bybee | Google Review
2. Medic Pharmacy – Compounding Pharmacy – Hefner Pointe

Website: https://www.medicokc.com/
Address: 11101 Hefner Pointe Drive, Suite 101
Contact: 405-755-3921 | Fax: 405-755-3922 | [email protected]
Hours: Monday-Friday, 9:00 AM-6:00 PM; Saturday, 9:00 AM-1:00 PM
Operating since 1998, Medic Pharmacy is a family-run compounding pharmacy that creates custom medications for people and household pets.
They specialize in veterinary formulations, pain management blends, and hormone replacement therapies.
To make regular prescriptions easier to manage, their team offers refill synchronization, so you can pick up your monthly maintenance medications in one visit.
If you don’t want to make another trip across town, you can even request Priority Mail shipping.
They also provide routine immunizations, including flu and shingles vaccines, on-site.
Just keep their local delivery rules in mind, since home delivery costs $7.50 and is available Monday through Friday from 2:00 PM to 6:00 PM only.
Customer Reviews
Hands down THE. BEST. PHARMACY. IN. TOWN
Always amazing service with quality professionals working to fill my medication needs and more. At Medic all of their staff takes a proactive step with my health care needs going above and beyond to make sure I’m actively filling my body what it needs and never allowing me to purchase anything unnecessary thus keeping my costs down. I can’t say it enough…Hands down THE. BEST. PHARMACY. IN. TOWN.
— Sheri Clanin | Google Review
Medic remains the best pharmacy in NW OKC
Medic remains the best pharmacy in NW OKC, simply because of the care, concern and customer service. It reminds me of the place my parents used to use decades ago. They know you by name, ask all the right questions and go above and beyond.
— Dave F | Google Review
3. Bristol Pharmacy Oklahoma

Website: https://www.rxbristolokc.com/
Address: 10717 N May Avenue, Suite D, The Village
Contact: (405) 451-0777 | Fax: (405) 451-0778 | [email protected]
Hours: Monday-Friday, 9:00 AM-5:00 PM
Bristol Pharmacy Oklahoma focuses on dermatology, eye care, and women’s health while offering free prescription shipping throughout the state. Their staff handles routine prescriptions along with specialty medications.
To help you save, their team compares available cash prices and savings offers with your insurance company. This gives you a clearer idea of which option may cost less.
They also work with prescribers to help coordinate prior authorizations, and you can place orders over the phone without downloading extra software.
However, parcel delivery typically takes one to three business days and may take longer for distant addresses. So, if your prescription is urgent, don’t rely on shipping for guaranteed same-day arrival.
Customer Reviews
Everyone is knowledgeable, kind, and willing to go the extra mile
I can’t say enough good things about Bristol pharmacy! The staff knows our family by name (and often by sight), and they always make us feel genuinely cared for. Everyone is knowledgeable, kind, and willing to go the extra mile to answer questions or help solve a problem. They also offer convenient pickup, delivery, and mailing services, which has been such a blessing. It’s refreshing to find a locally owned business that provides this level of personal service. We wouldn’t want to go anywhere else!
— Dana Wilson | Google Review
I cannot recommend this pharmacy enough
This is the best pharmacy. I use their services through an app called Nimble and it has made my life so much easier. The people here are amazing and always make sure I have my medications on time. A special shout out to Katie K who left a nice note explaining my insurance covered my medications. I cannot recommend this pharmacy enough.
— Whitney Kleinpeter | Google Review
4. United Discount Pharmacy

Website: https://www.uniteddiscountrx.com/
Address: 5420 N Portland Avenue
Contact: 405-947-6828 | Fax: 405-946-3346 | [email protected]
Hours: Monday-Friday, 9:00 AM-6:00 PM; Saturday, 9:00 AM-2:00 PM
Serving the metro area since 1982, United Discount Pharmacy provides custom non-sterile compounding, mobile vaccination services, and organized medication packaging.
Their pharmacy team can prepare custom strengths and medicated oral rinses for specific prescription needs.
We spoke with their pharmacist about the organized blister cards, and he showed us how clearly each dosage slot is labeled.
Beyond packaging, their staff also travels to local senior communities and workplaces to administer group vaccines. Their online patient portal makes tracking refills easier for family caregivers, too.
However, Saturday service ends at 2:00 PM, and Sunday pickup isn’t available. So, plan ahead if you need medications over the weekend or for an urgent prescription.
Customer Reviews
Best pharmacy in Oklahoma City!!!
Best pharmacy in Oklahoma City!!! They have the mom and pop store feeling and go out of the way to make sure you get everything you need at the lowest possible cost!!!! Absolutely love them!!!
— F Tt | Google Review
Best pharmacy in the state
Best pharmacy in the state ,loving, caring, friendly staff who are more like family than anything .. I wouldn’t ever get a prescription filled anywhere else ever. Oklahoma owned and ran , ma and pop-like pharmacy the way businesses used to be.. I wish I could do all my shopping here honestly , I love this place , it’s my 1# I’ve been going here for 20 years !!
— Erica Ducay | Google Review
5. Nichols Hills Drug

Website: https://nicholshillsdrug.com/
Address: 7600 N Western Avenue, Nichols Hills
Contact: (405) 843-9501 | Fax: (405) 842-8535
Hours: Monday-Friday, 9:00 AM-6:00 PM; Saturday, 9:00 AM-1:00 PM
Nichols Hills Drug is a welcoming neighborhood pharmacy that combines synchronized monthly refills with organized pill packaging and curbside pickup.
Their pharmacists also work with your doctor on custom formulations, including different strengths or removing unwanted ingredients when appropriate.
To make daily medications easier to manage, they organize prescriptions into clearly labeled packages that can help keep your treatment on track.
If you’re feeling under the weather, just phone the front desk when you arrive, and they’ll carry your bag straight to your vehicle.
Unfortunately, their $3.99 local delivery is limited to a five-mile radius from the shop, although separate courier shipping is available for addresses farther away.
Customer Reviews
The finest and most knowledgeable group of Pharmacists
To all who take the opportunity to read this, my personal review and opinion is that Nichols Hills Drug Pharmacy and staff are the finest and most knowledgeable group of Pharmacists that care to the medical needs of myself and family. I thank them for their continued exceptional and professional service.
— Chris Askren | Google Review
Our pharmacy of choice for decades
Nichols Hills Drug has been our pharmacy of choice for decades. They have gone from a Mom & Pop pharmacy to a modernized operation while maintaining the integrity of small town friendliness! We look forward to many more happy years seeing Myia and staff!
— Michelle Stockbridge | Google Review





